The data revealed the mRNA-loaded polyplex nanomicelle was instantly engulfed by cellular late endosome, then unfold into the cytosol homogeneously at a amount of lower than twenty min publish-administration in the mRNA medicine. The mRNA expression persisted for at least 6-days post-injection in vivo. On top of that, the Runx1 https://www.directivepublications.org/the-journal-of-molecular-biology/