Schematic representation of activated and inhibited Wnt/β-catenin pathway. “WNT ON state�? Upon ligation of Wnts for their receptors composed of frizzled proteins and LRP5/six, the cytoplasmic protein DVL is activated and induces the suppression of GSK3β. Subsequently, stabilized β-catenin translocates in to the nucleus and binds to TCF/LEF transcription elements https://juliushorsr.collectblogs.com/74372407/facts-about-schisandrol-b-revealed