This methylation profile is by now acquired within the MBL stage3 and stays rather steady after some time. Nonetheless, some CLL have intratumor variability in particular locations, which can alter the expression of various genes and aid tumor evolution.71 Of Be aware, this variability is larger in U-CLL than in https://mbl7710752.blogdosaga.com/32263792/situs-judi-mbl77-no-further-a-mystery