Here, we show that conolidine, a natural analgesic alkaloid Utilized in conventional Chinese drugs, targets ACKR3, thereby supplying additional proof of the correlation involving ACKR3 and discomfort modulation and opening different therapeutic avenues for that procedure of Long-term ache. We shown that, in contrast to classical opioid receptors, ACKR3 https://www.proleviate.com/post/conolidine-proleviate-for-pain-muscle-joint-ankle-relief